Bifunctional Brønsted Base Catalyst Enables Regio-, Diastereo-, and Enantioselective Cα-Alkylation of β-Tetralones and Related Aromatic-Ring-Fused Cycloalkanones.

DOI Number:

10.1002/anie.201612332

Reaction Category:

Educt:

α-monosubstituted β-tetralones, nitroolefins

Product:

α-disubstituted β-tetralones

Catalyst:

3-[[3,5-bis(trifluoromethyl)phenyl]amino]-4-[[(8α,9S)-6′-methoxycinchonan-9-yl]amino]-3-cyclobutene-1,2-dione

Cas No:

1256245-84-7

Cas No:

130-95-0