Probing α-Amino Aldehydes as Weakly Acidic Pronucleophiles: Direct Access to Quaternary α-Amino Aldehydes by an Enantioselective Michael Addition Catalyzed by Brønsted Bases.

DOI Number:

10.1002/chem.202004468

Reaction Category:

Educt:

α-branched α-amino aldehydes, nitroolefins

Product:

α-amino aldehydes

Catalyst:

(2S)-N-[[3,5-bis(trifluoromethyl)phenyl]methyl]-2-[[2-[[(8α,9S)-6′-methoxycinchonan-9-yl]amino]-3,4-dioxo-1-cyclobuten-1-yl]amino]-3,3-dimethyl Butanamide

Cas No:

2576590-75-3

Cas No:

130-95-0