syn-Selective Michael Reaction of α-Branched Aryl Acetaldehydes with Nitroolefins Promoted by Squaric Amino Acid Derived Bifunctional Brønsted Bases.
DOI Number:
10.1002/ejoc.202100355
Reaction Category:
RXNO ID:
RXNO_0000009
Educt:
α‐branched aryl acetaldehydes, nitroolefins
Product:
2,2,3‐trisubstituted syn γ‐nitroaldehydes
Catalyst:
(S)-N-((S)-3,3-dimethyl-1-oxo-1-(piperidin-1-yl)butan-2-yl)-2-((2-(((S)-(6-methoxyquinolin-4-yl)((1S,2S,4S,5R)-5-vinylquinuclidin-2-yl)methyl)amino)-3,4-dioxocyclobut-1-en-1-yl)amino)-3,3-dimethylbutanamide
Cas No:
2692606-17-8
Associated Product from Buchler GmbH:
Quinine Base
Cas No:
130-95-0