Asymmetric Mannich Reactions of Ketones with Isatin-Derived N-Unprotected Ketimines Catalyzed by Amine Derivatives.

DOI Number:

10.1021/acs.joc.6c01844
Link to literature

Reaction Category:

Mannich | Mannich

RXNO ID:

RXNO_0000032

Educt:

isatin-derived N-unprotected ketimines, ketones

Product:

substituted 3-amino-3-(2-oxoethyl)indolin-2-one

Catalyst:

2-hydroxypropane-1,2,3-tricarboxylic acid, (8α,9S)-Cinchonan-9-amine

Cas No:

850409-61-9

Associated Product from Buchler GmbH:

Cinchonidine Base

Cas No:

485-71-2