Squaramide-catalysed enantionselective Mannich reaction of imines bearing a heterocycle with malonates.

DOI Number:

10.1039/C3RA43260B
Link to literature

Reaction Category:

Mannich | Mannich

RXNO ID:

RXNO_0000032

Educt:

imines, malonates

Product:

substituted dimethyl 2-(aminomethyl)malonate

Catalyst:

3-[[3,5-bis(trifluoromethyl)phenyl]amino]-4-[[(8α,9S)-6′-methoxycinchonan-9-yl]amino]-3-Cyclobutene-1,2-dione

Cas No:

1256245-84-7

Associated Product from Buchler GmbH:

3-[[3,5-bis(trifluoromethyl)phenyl]amino]-4-[[(8α,9S)-6′-methoxycinchonan-9-yl]amino]-3-Cyclobutene-1,2-dione

Cas No:

1256245-84-7