Asymmetric approach toward chiral cyclohex-2-enones from anisoles via an enantioselective isomerization by a new chiral diamine catalyst.

DOI Number:

10.1021/ja308623n
Link to literature

Reaction Category:

Isomerization

MOP ID:

MOP_0000789

Educt:

5,5-dimethyl-3,4,5,6,7,8-hexahydronaphthalen-2(1H)-one

Product:

(S)-5,5-dimethyl-4,4a,5,6,7,8-hexahydronaphthalen-2(3H)-one

Catalyst:

(R)-2-chloropropanoic acid, N1-[(9R)-6′-methoxycinchonan-9-yl]-4-(trifluoromethyl)-1,2-benzenediamine

Cas No:

1404088-26-1

Associated Product from Buchler GmbH:

Quinidine Base

Cas No:

56-54-2