Cinchona-derived thiourea catalyzed hydrophosphonylation of ketimines-An enantioselective synthesis of α-amino phosphonates.

DOI Number:

10.1016/j.tet.2014.06.013
Link to literature

Reaction Category:

Hydrophosphonylation

Educt:

substituted tert-butyl (E)-(2-oxoindolin-3-ylidene)carbamate, diphenyl phosphite

Product:

substituted tert-butyl (R)-(3-(diphenoxyphosphoryl)-2-oxoindolin-3-yl)carbamate

Catalyst:

N-[3,5-Bis(trifluoromethyl)phenyl]-N′-(8α,9S)-cinchonan-9-ylthiourea

Cas No:

890044-38-9

Associated Product from Buchler GmbH:

Cinchonidine Base

Cas No:

485-71-2