Asymmetric synthesis of alkyl 5-oxotetrahydrofuran-2-carboxylates by enantioselective hydrogenation of dialkyl 2-oxoglutarates over cinchona modified Pt/Al2O3 catalysts.

DOI Number:

10.1039/b9000390p

Reaction Category:

MOP ID:

MOP_0000589

Educt:

diethyl 2-oxopentanedioate, hydrogen, p-toluenesulfonic acid

Product:

ethyl (R)-5-oxotetrahydrofuran-2-carboxylate

Catalyst:

platinum/aluminiumoxide, (8α,9R)-10,11-Dihydro-9-methoxycinchonan

Cas No:

129960-94-7

Cas No:

485-64-3