Catalyst-free and catalytic Friedel–Crafts alkylations of indoles in Solkane 365mfc, an environmentally benign alternative solvent.

DOI Number:

10.1039/c0gc00619j

Reaction Category:

RXNO ID:

RXNO_0000369

Educt:

7-methylindole, ethyl 2-oxoacetate

Product:

ethyl 2-hydroxy-2-(7-methyl-1H-indol-3-yl)-2lambda3-ethanoate

Catalyst:

9-[[4-(1,1,2,2,3,3,4,4,5,5,6,6,7,7,8,8,8-heptadecafluorooctyl)phenyl]methoxy]- (9S)-Cinchonan-6′-ol

Cas No:

1265815-58-4

Cas No:

70877-75-7