Enantioselective monofluoromethylation of aldehydes with 2-fluoro-1,3-benzodithiole-1,1,3,3-tetraoxide catalyzed by a bifunctional cinchona alkaloid-derived thiourea–titanium complex.
DOI Number:
10.1039/C3CC46544F
Reaction Category:
MOP ID:
MOP_0000553
Educt:
aldehydes, 2-fluoro-2H-benzo[d][1,3]dithiole 1,1,3,3-tetraoxide
Product:
monofluoromethylated-adducts
Catalyst:
tetraisopropoxytitanium, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-hydroxycinchonan-9-yl]thiourea
Cas No:
1313811-71-0
Associated Product from Buchler GmbH:
Cupreine Base
Cas No:
524-63-0