Enantioselective synthesis of cis-3-fluoropiperidin-4-ol, a building block for medicinal chemistry.

DOI Number:

10.1021/jo401352z

Reaction Category:

Educt:

protected piperidin-4-one, N-fluoro-N-(phenylsulfonyl)benzenesulfonamide

Product:

cis-3-fluoropiperidin-4-ol

Catalyst:

trichloroacetic acid, (8α,9S)-6′-Methoxycinchonan-9-amine

Cas No:

168960-95-0

Cas No:

130-95-0