Enantioselective Organocatalyzed aza-Michael Addition Reaction of 2-Hydroxybenzophenone Imines to Nitroolefins under Batch and Flow Conditions.
DOI Number:
10.1002/adsc.202100635
Reaction Category:
RXNO ID:
RXNO_0000009
Educt:
2-hydroxybenzophenone imine, (E)-(2-nitrovinyl)benzene
Product:
(R,E)-2-(((2-nitro-1-phenylethyl)imino)(phenyl)methyl)phenol
Catalyst:
N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea
Cas No:
852913-16-7
Associated Product from Buchler GmbH:
Quinine Base
Cas No:
130-95-0