One‐Pot Catalytic Synthesis of Optically Active Drug (S)‐Clopidogrel.

DOI Number:

10.1002/ejoc.202300744
Link to literature

Reaction Category:

Epoxidation

MOP ID:

MOP_0000671

Educt:

(E)-3-(2-chlorophenyl)-2-(naphthalen-1-ylsulfonyl)acrylonitril, tert-butyl hydroperoxide

Product:

(2R,3R)-3-(2-chlorophenyl)-2-(naphthalen-1-ylsulfonyl)oxirane-2-carbonitrile

Catalyst:

N-[(1R,2R)-2-amino-1,2-di-1-naphthalenylethyl]-N′-[(9R)-6′-methoxycinchonan-9-yl]-thiourea

Cas No:

2088845-68-3

Associated Product from Buchler GmbH:

Quinidine Base

Cas No:

56-54-2