Hydrogen‐Bond‐Enabled Dynamic Kinetic Resolution of Axially Chiral Amides Mediated by a Chiral Counterion.

DOI Number:

10.1002/anie.201814362
Link to literature

Reaction Category:

Dynamic Kinetic Resolution | Resolution

Educt:

substituted 2-hydroxy-N,N-disubstituted-1-naphthamide, benzyl iodide

Product:

substituted 2-(benzyloxy)-N,N-disubstituted-1-naphthamide

Catalyst:

(9S)-9-hydroxy-1-[[2,3′′,4,5′′-tetrakis(1,1-dimethylethyl)[1,1′:3′,1′′-terphenyl]-5′-yl]methyl]-cinchonanium bromide

Cas No:

2292262-87-2

Associated Product from Buchler GmbH:

Cinchonine Base

Cas No:

118-10-5