Organocatalytic asymmetric addition of alcohols and thiols to activated electrophiles: efficient dynamic kinetic resolution and desymmetrization protocols.

DOI Number:

10.1021/jo801158g

Reaction Category:

Educt:

4-methyldihydro-2H-pyran-2,6(3H)-dione, cyclohexanethiol

Product:

5-(cyclohexylthio)-3-methyl-5-oxopentanoic acid

Catalyst:

N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea

Cas No:

852913-16-7

Associated Product from Buchler GmbH:

N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea

Cas No:

852913-16-7