Highly enantioselective decarboxylative protonation of α-aminomalonates mediated by thiourea Cinchona alkaloid derivatives: Access to both enantiomers of cyclic and acyclic α-aminoacids.
DOI Number:
10.1021/ol070712v
Reaction Category:
Educt:
subtituted 2-(ethoxycarbonyl)-4-oxopentanoic acid
Product:
2R-substituted ethyl 4-oxopentanoate
Catalyst:
N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea
Cas No:
852913-16-7
Associated Product from Buchler GmbH:
Quinine Base
Cas No:
130-95-0