Towards a universal organocatalyst for the synthesis of enantioenriched phenylalanine derivatives by enantioselective decarboxylative protonation.

DOI Number:

10.1016/j.tetlet.2016.09.001
Link to literature

Reaction Category:

Decarboxylative Protonation | Protonation

Educt:

2-acetamido-2-benzyl-3-ethoxy-3-oxopropanoic acid

Product:

ethyl acetyl-L-phenylalaninate

Catalyst:

N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(9R)-6′-methoxycinchonan-9-yl]thiourea

Cas No:

852913-25-8

Associated Product from Buchler GmbH:

N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(9R)-6′-methoxycinchonan-9-yl]thiourea

Cas No:

852913-25-8