A quinine squaramide catalyzed enantioselective [4+2] cycloaddition between ortho-hydroxyphenyl para-quinone methide and γ-butenolides for preparation of chiral 3,4-dihydrocoumarins.
DOI Number:
10.1016/j.tetlet.2024.155311
Reaction Category:
MOP ID:
MOP_0000565
Educt:
γ-butenolides, ortho-hydroxyphenyl para-quinone methide
Product:
(3S,4S)-3-(2-(4-chlorophenyl)-2-oxoethyl)-4-(3,5-di-tert-butyl-4-hydroxyphenyl)chroman-2-one
Catalyst:
3-[[[3,5-Bis(trifluoromethyl)phenyl]methyl]amino]-4-[[(8α,9S)-6′-methoxycinchonan-9-yl]amino]-3-Cyclobutene-1,2-dione
Cas No:
1210360-60-3
Associated Product from Buchler GmbH:
3-[[[3,5-Bis(trifluoromethyl)phenyl]methyl]amino]-4-[[(8α,9S)-6′-methoxycinchonan-9-yl]amino]-3-Cyclobutene-1,2-dione
Cas No:
1210360-60-3