Enantioselective synthesis of trifluoromethyl‐substituted 2‐isoxazolines: asymmetric hydroxylamine/enone cascade reaction.

DOI Number:

10.1002/anie.201002065
Link to literature

Reaction Category:

Cascade reaction | Cyclization | Cyclization | Further Cyclizations

MOP ID:

MOP_0000561

Educt:

substituted (E)-5,5,5-trifluoropent-3-en-2-one, hydroxylamine

Product:

trifluoromethyl‐substituted 2‐isoxazolines

Catalyst:

1-[[3,5-bis(trifluoromethyl)phenyl]methyl]-9-hydroxy-6′-methoxy-cinchonanium bromide

Cas No:

945732-76-3

Associated Product from Buchler GmbH:

Quinidine Base

Cas No:

56-54-2