Organocatalytic Activation of Diethyl Glutaconate for the Diastereo-and Enantioselective Assembly of NH-Free 2, 3, 4-Trisubstituted Pyrrolidines.
DOI Number:
10.1021/acs.orglett.7b00014
Reaction Category:
MOP ID:
MOP_0000561
Educt:
diethyl (E)-pent-2-enedioate, (E)-(2-nitrovinyl)benzene
Product:
ethyl (2R,3S,4R)-2-(2-ethoxy-2-oxoethyl)-4-phenylpyrrolidine-3-carboxylate
Catalyst:
N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea
Cas No:
852913-16-7
Associated Product from Buchler GmbH:
N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea
Cas No:
852913-16-7