Synergistic promotion by intramolecular hydrogen bonding: a bi-functionally catalyzed cascade reaction for the synthesis of enantiopure chromenopyrrolidines.

DOI Number:

10.1039/C8QO01208C

Reaction Category:

MOP ID:

MOP_0000561

Educt:

diethyl (E)-2-((2-hydroxybenzylidene)amino)malonate, benzyl (E)-2-oxo-4-phenylbut-3-enoate

Product:

chromenopyrrolidines

Catalyst:

N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea

Cas No:

852913-16-7

Associated Product from Buchler GmbH:

N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea

Cas No:

852913-16-7