Organocatalyzed enantioselective synthesis of 2-amino-5-oxo-5,6,7,8-tetrahydro-4H-chromene-3-carboxylates.

DOI Number:

10.1016/j.tetlet.2011.10.040
Link to literature

Reaction Category:

Cyclization | Cyclization | Further Cyclizations | Michael | Michael Addition

MOP ID:

MOP_0000561

Educt:

5,5-disubstituted cyclohexane-1,3-dione, (E)-2-cyano-3-phenylacrylate

Product:

2-amino-5-oxo-5,6,7,8-tetrahydro-4H-chromene-3-carboxylates

Catalyst:

N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea

Cas No:

852913-16-7

Associated Product from Buchler GmbH:

N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea

Cas No:

852913-16-7