The first organocatalytic asymmetric synthesis of 3-substituted isoindolinones.

DOI Number:

10.1039/C2RA20231J
Link to literature

Reaction Category:

Cyclization | Cyclization | Further Cyclizations

MOP ID:

MOP_0000561

Educt:

2-formylbenzonitrile, diisopropyl malonate

Product:

3-substituted isoindolinones

Catalyst:

N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea

Cas No:

852913-16-7

Associated Product from Buchler GmbH:

N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea

Cas No:

852913-16-7