Organocatalytic Asymmetric Synthesis of Trifluoromethyl‐substituted Diarylpyrrolines: Enantioselective Conjugate Cyanation of β‐Aryl‐β‐trifluoromethyl‐disubstituted Enones.
DOI Number:
10.1002/anie.201201278
Reaction Category:
MOP ID:
MOP_0000597
Educt:
substituted (E)-4,4,4-trifluorobut-2-enoyl, 2-hydroxy-2-methylpropanenitrile
Product:
substituted (R)-3-cyano-4,4,4-trifluorobutanoyl
Catalyst:
(9S)-1-[[2,5-bis(trifluoromethyl)phenyl]methyl]-6′,9-dimethoxy-cinchonanium bromide
Cas No:
1380297-63-1
Associated Product from Buchler GmbH:
Quinidine Base
Cas No:
56-54-2