Catalytic Asymmetric Imine Cross-Coupling Reaction.

DOI Number:

10.1021/jacs.3c00051
Link to literature

Reaction Category:

Cross Coupling

Educt:

(Z)-N-(4-nitrobenzyl)-4-(triisopropylsilyl)but-3-yn-2-imine, methyl (E)-benzylidenecarbamate

Product:

methyl ((1S,2R)-2-methyl-2-(((E)-4-nitrobenzylidene)amino)-1-phenyl-4-(triisopropylsilyl)but-3-yn-1-yl)carbamate, methyl (E)-(2-(4-nitrophenyl)-1-phenyl-2-((4-(triisopropylsilyl)but-3-yn-2-ylidene)amino)ethyl)carbamate

Catalyst:

9-[(6-chloro-2,5-diphenyl-4-pyrimidinyl)oxy]-1-[[2′-(1,1-dimethylethoxy)-3,3′′,5,5′′-tetramethoxy[1,1′:3′,1′′-terphenyl]-5′-yl]methyl]-10,11-dihydro-11-[[tris(1-methylethyl)silyl]oxy]-(9R)-cinchonanium bromide

Cas No:

2909537-54-6

Associated Product from Buchler GmbH:

Cinchonidine Base

Cas No:

485-71-2