Organocatalytic Asymmetric Dearomatization of 3-Nitroindoles and 3-Nitrobenzothiophenes via Thiol-Triggered Diastereo- and Enantioselective Double Michael Addition Reaction.

DOI Number:

10.1021/acs.orglett.9b01688

Reaction Category:

RXNO ID:

RXNO_0000009

Educt:

ethyl (E)-4-mercaptobut-2-enoate, 3-nitrobenzothiophene

Product:

tetrahydrothiophenebenzothiophene

Catalyst:

(αR)-α-[[[[3,5-Bis(trifluoromethyl)phenyl]amino]thioxomethyl]amino]-N-[(8α,9S)-6′-methoxycinchonan-9-yl]benzenepropanamide

Cas No:

1509940-73-1

Cas No:

130-95-0