Catalytic enantioselective synthesis of β-trifluoromethyl pyrrolines.
DOI Number:
10.1039/C2CC18049A
Reaction Category:
Educt:
(E)-4,4,4-trifluoro-1-(4-methoxyphenyl)but-2-en-1-one, nitromethane
Product:
(S)-5-(4-methoxyphenyl)-3-(trifluoromethyl)-3,4-dihydro-2H-pyrrole
Catalyst:
iron, acetic acid, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-(8α,9S)-cinchonan-9-ylthiourea
Cas No:
890044-38-9
Associated Product from Buchler GmbH:
Cinchonidine Base
Cas No:
485-71-2