C–H Oxidation/Michael Addition/Cyclization Cascade for Enantioselective Synthesis of Functionalized 2-Amino-4H-chromenes.

DOI Number:

10.1021/acs.orglett.5b03148
Link to literature

Reaction Category:

Cascade reaction

Educt:

2-alkyl-substituted phenols, active methylene compounds bearing a cyano group

Product:

2-amino-4H-chromenes

Catalyst:

3-[[3,5-bis(trifluoromethyl)phenyl]amino]-4-[[(8α,9S)-6′-methoxycinchonan-9-yl]amino]-3-Cyclobutene-1,2-dione

Cas No:

1256245-84-7

Associated Product from Buchler GmbH:

Quinine Base

Cas No:

130-95-0