Enantioselective synthesis and evaluation of 4-styryldihydropyrimidin-2-thiones as anti-proliferative agents.

DOI Number:

10.1007/s00044-017-1790-4

Reaction Category:

RXNO ID:

RXNO_0000236

Educt:

cinnamaldehydes, thiourea, b-keto-esters

Product:

4-styryldihydropyrimidin-2-thiones

Catalyst:

(1R,3S,5R)-2-Azabicyclo[3.1.0]hexane-3-carboxylic acid, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea

Cas No:

852913-16-7

Associated Product from Buchler GmbH:

N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea

Cas No:

852913-16-7