Asymmetric Azide–Alkyne Cycloaddition with Ir (I)/Squaramide Cooperative Catalysis: Atroposelective Synthesis of Axially Chiral Aryltriazoles.

DOI Number:

10.1021/jacs.2c02563
Link to literature

Reaction Category:

Addition | Cyclization | Cycloaddition

MOP ID:

MOP_0000562

Educt:

1-(substituted-ethynyl)naphthalen-2-ol, azidoalkane

Product:

1-(1,4-substituted-1H-1,2,3-triazol-5-yl)naphthalen-2-ol

Catalyst:

3-[[3,5-bis(trifluoromethyl)phenyl]amino]-4- [[(8α,9S)-6′-methoxycinchonan-9-yl]amino]- 3-Cyclobutene-1,2-dione

Cas No:

1256245-84-7

Associated Product from Buchler GmbH:

Quinine Base

Cas No:

130-95-0