Organocatalyzed Enantioselective Aza-Morita–Baylis–Hillman Reaction of Cyclic Ketimine with α, β-Unsaturated γ-Butyrolactam.

DOI Number:

10.1021/acs.joc.2c02765

Reaction Category:

RXNO ID:

RXNO_0000076

Educt:

cyclic ketimines, α,β-unsaturated γ-butyrolactam

Product:

substituted tert-butyl (R)-2-oxo-3-(3-oxo-2-phenylindolin-2-yl)-2,5-dihydro-1H-pyrrole-1-carboxylate

Catalyst:

N-[3,5-bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-10,11-dihydro-6′-methoxy-cinchonan-9-yl]-Thiourea

Cas No:

852913-19-0

Cas No:

522-66-7