Metal-free and enantioselective synthesis of 1,4-benzoxazepines from para-quinone methide derivatives and α-bromohydroxamates.

DOI Number:

10.1039/D3CC02368K

Reaction Category:

RXNO ID:

RXNO_0000009

Educt:

para-quinone methide derivatives, α-bromohydroxamates

Product:

(S)-N-(benzyloxy)-2-bromo-N-((3,5-di-tert-butyl-4-hydroxyphenyl)(2-hydroxyphenyl)methyl)acetamide

Catalyst:

3-[[3,5-Bis(trifluoromethyl)phenyl]amino]-4-[[(9R)-6′-methoxycinchonan-9-yl]amino]-3-cyclobutene-1,2-dione

Cas No:

1256245-79-0

Associated Product from Buchler GmbH:

3-[[3,5-bis(trifluoromethyl)phenyl]amino]-4-[[(9R)-6′-methoxycinchonan-9-yl]amino]-3-Cyclobutene-1,2-dione

Cas No:

1256245-79-0