An enantioselective aza-Henry reaction of trifluoromethyl ketimines catalyzed by phase-transfer catalysts.

DOI Number:

10.1039/C9QO00850K
Link to literature

Reaction Category:

Aza-Henry | Henry | Mannich | Nitro-Mannich

RXNO ID:

RXNO_0000235

Educt:

trifluoromethyl ketimines, nitromethane

Product:

tert-butyl (S)-(1,1,1-trifluoro-3-nitro-2-substituted-propan-2-yl)carbamate

Catalyst:

(8α,9S)-1-[[3,5-bis(1,1-dimethylethyl)phenyl]methyl]-9-[[[[(1S)-2-hydroxy-1-phenylethyl]amino]carbonyl]amino]-6′-methoxy-cinchonanium bromide

Cas No:

2095003-15-7

Associated Product from Buchler GmbH:

Quinine Base

Cas No:

130-95-0