Supported Bifunctional Chiral Thioureas as Catalysts in the Synthesis of 3-Amino-2-Oxindoles through Enantioselective aza-Friedel-Crafts Reaction: Application in Continuous Flow Processes.

DOI Number:

10.1002/adsc.202000238

Reaction Category:

Educt:

tert-butyl (E)-(1-benzyl-2-oxoindolin-3-ylidene)carbamates, naphthols

Product:

tert-butyl (R)-(1-benzyl-3-(1-hydroxynaphthalen-2-yl)-2-oxoindolin-3-yl)carbamates

Catalyst:

N-[(8α,9S)-10,11-dihydro-6′-methoxycinchonan-9-yl]-Thiourea (aminoalkyl polystyrene resin-supported)

Cas No:

2418549-11-6

Cas No:

522-66-7