Atroposelective synthesis of eight-membered lactam-bridged N-arylindoles via stepwise cut-and-sew strategy.

DOI Number:

10.1016/j.xcrp.2023.101697
Link to literature

Reaction Category:

Atropisomer synthesis

Educt:

tert-butyl 7-bromo-1-methyl-6-oxoindolo[1,2-a]quinoxaline-5(6H)-carboxylate, ethyl 2-isocyanoacetate

Product:

lactam-bridged N-arylindoles

Catalyst:

2-(diphenylphosphino)-N-[(8α,9S)-6′-methoxycinchonan-9-yl]-benzamide

Cas No:

1630973-03-3

Associated Product from Buchler GmbH:

Quinine Base

Cas No:

130-95-0