Catalytic enantioselective synthesis of atropisomeric biaryls by a cation-directed O-alkylation.
DOI Number:
10.1038/nchem.2710
Reaction Category:
MOP ID:
MOP_0000369
Educt:
O/C-substituted 2'-hydroxy-3,4-dihydro-[1,1'-binaphthalen]-2(1H)-one, benzyl iodide
Product:
atropisomeric biaryls
Catalyst:
(9S)-9-hydroxy-6′-methoxy-1-[(2,3,4-trifluorophenyl)methyl]-cinchonanium bromide
Cas No:
949028-87-9
Associated Product from Buchler GmbH:
Quinidine Base
Cas No:
56-54-2