Catalytic asymmetric and divergent synthesis of tricyclic and tetracyclic spirooxindoles: Controllable site-selective electrophilic halocyclization of 1,6-enynes.

DOI Number:

10.1021/acs.orglett.9b02202

Reaction Category:

MOP ID:

MOP_0000369

Educt:

N-protected 3-allylindolin-2-one, N-protected 1-ethoxy-3-phenylprop-2-yn-1-amine

Product:

pyrazoles

Catalyst:

N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea

Cas No:

852913-16-7

Associated Product from Buchler GmbH:

N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea

Cas No:

852913-16-7