Enantioselective synthesis of β-hydroxy-α-amino acid esters by aldol coupling using a chiral quaternary ammonium salt as catalyst.

DOI Number:

10.1016/S0040-4039(99)00636-X

Reaction Category:

Educt:

(Z)-N-(2-(tert-butoxy)-2-((trimethylsilyl)oxy)vinyl)-1,1-diphenylmethanimine, heptanal

Product:

tert-butyl (2S,3R)-2-amino-3-hydroxynonanoate

Catalyst:

1-(9-anthracenylmethyl)-9-(phenylmethoxy)-(8α,9R)-cinchonanium hydrogen difluoride

Cas No:

228868-82-4

Cas No:

485-71-2