Cinchona-Alkaloid-Catalyzed Enantioselective Direct Aldol-Type Reaction of Oxindoles with Ethyl Trifluoropyruvate.
DOI Number:
10.1002/anie.200703317
Reaction Category:
RXNO ID:
RXNO_0000016
Educt:
oxindoles, ethyl trifluoropyruvate
Product:
ethyl 2-(5-substituted-3-substituted-2-oxoindolin-3-yl)-3,3,3-trifluoro-2-hydroxypropanoate
Catalyst:
(8α,9R)-(8′′α,9′′R)-9,9′′-[1,4-Phthalazinediylbis(oxy)]bis[10,11-dihydro-6′-methoxycinchonan] ((DHQ)2PHAL
Cas No:
140924-50-1
Associated Product from Buchler GmbH:
1,4-Bis(9-O-dihydroquininyl)phthalazine ((DHQ)2PHAL
Cas No:
140924-50-1