Enantioselective primary amine catalyzed aldol-type construction of trifluoromethylated tertiary alcohols.

DOI Number:

10.1055/s-0033-1341281
Link to literature

Reaction Category:

Aldol | Aldol

RXNO ID:

RXNO_0000016

Educt:

(hetero)-aryl-trifluoromethyl-ketones, methylketones

Product:

substituted (R)-4-aryl-5,5,5-trifluoro-4-hydroxy-pentan-2-one

Catalyst:

(8α,9S)-6′-Methoxycinchonan-9-amine

Cas No:

168960-95-0

Associated Product from Buchler GmbH:

Quinine Base

Cas No:

130-95-0