Enantioselective monofluoromethylation of aldehydes with 2-fluoro-1, 3-benzodithiole-1, 1, 3, 3-tetraoxide catalyzed by a bifunctional cinchona alkaloid-derived thiourea–titanium complex.
DOI Number:
10.1039/C3CC46544F
Reaction Category:
RXNO ID:
RXNO_0000016
Educt:
aldehydes, 2-fluoro-2H-benzo[d][1,3]dithiole 1,1,3,3-tetraoxide
Product:
primary 2-fluoroalcohols
Catalyst:
tetraisopropoxytitanium, N-[3,5-bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-hydroxycinchonan-9-yl]-thiourea
Cas No:
1313811-71-0
Associated Product from Buchler GmbH:
Cupreine Base
Cas No:
524-63-0