The squaramidecatalyzed 1,3-dipolar cycloaddition of nitroalkenes with N-2,2,2-trifluoroethylisatin ketimines: An approach for the synthesis of 50-trifluoromethyl-spiro[pyrrolidin-3,20-oxindoles].
DOI Number:
10.1039/C6CC06367E
Reaction Category:
MOP ID:
MOP_0000715
Educt:
3-alkenyl-5-arylfuran-2 (3 H)-ones, N-2,2,2-trifluoroethylisatin ketimines
Product:
spiro[pyrrolidin-3,2′-oxindoles]
Catalyst:
N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea
Cas No:
852913-16-7
Associated Product from Buchler GmbH:
N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea
Cas No:
852913-16-7