The squaramidecatalyzed 1,3-dipolar cycloaddition of nitroalkenes with N-2,2,2-trifluoroethylisatin ketimines: An approach for the synthesis of 50-trifluoromethyl-spiro[pyrrolidin-3,20-oxindoles].

DOI Number:

10.1039/C6CC06367E

Reaction Category:

MOP ID:

MOP_0000715

Educt:

3-alkenyl-5-arylfuran-2 (3 H)-ones, N-2,2,2-trifluoroethylisatin ketimines

Product:

spiro[pyrrolidin-3,2′-oxindoles]

Catalyst:

N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea

Cas No:

852913-16-7

Associated Product from Buchler GmbH:

N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea

Cas No:

852913-16-7