Synthesis of 4-Fluoro-β-(4-fluorophenyl)-l-phenylalanine by an Asymmetric Phase-Transfer Catalyzed Alkylation:  Synthesis on Scale and Catalyst Stability.

DOI Number:

10.1021/op060190j

Reaction Category:

MOP ID:

MOP_0000369

Educt:

tert-butyl 2-((diphenylmethylene)amino)acetate, 4,4'-(bromomethylene)bis(fluorobenzene)

Product:

tert-butyl (S)-2-((diphenylmethylene)amino)-3,3-bis(4-fluorophenyl)propanoate

Catalyst:

O-Allyl-1-(anthracen-9-ylmethyl)-cinchonidinium Bromide

Cas No:

200132-54-3

Associated Product from Buchler GmbH:

O-Allyl-1-(anthracen-9-ylmethyl)-cinchonidinium Bromide

Cas No:

200132-54-3