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Michael Addition – Cyclization, methyl (R,E)-3-benzylidene-1-fluoro-2-oxocyclopentane-1-carboxylate, malononitrile, methyl (4S,7R)-2-amino-3-cyano-7-fluoro-4-phenyl-4,5,6,7-tetrahydrocyclopenta[b]pyran-7-carboxylate, 3-[[3,5-bis(trifluoromethyl)phenyl]amino]-4- [[(8α,9S)-6′-methoxycinchonan-9-yl]amino]- 3-Cyclobutene-1,2-dione, Quinine Derivative

by Anna-Lena Hartmann | Jun 23, 2023

Michael Addition, diketopiperazines, alpha,beta-unsaturated ketones, substituted methyl (S)-1,4-dibenzyl-3,5,6-trioxo-2-(3-oxopropyl)piperazine-2-carboxylate, (9S)-9-(phenylmethoxy)-cinchonan-6′-ol, Cupreidine Derivative

by werner@buchler-gmbh.com | Jun 15, 2023

Spirocyclization, (E)-3-arylenechroman-4-one or (E)-2-arylideneindan-1-one derivatives, bromo(nitro)methane, nitro-spirocyclopropanes, 3-[[3,5-Bis(trifluoromethyl)phenyl]amino]-4-[[(8α,9S)-10,11-dihydro-6′-methoxycinchonan-9-yl]amino]-3-Cyclobutene-1,2-dione, Dihydroquinine Derivative

by Anna-Lena Hartmann | Jun 15, 2023

Bromination, substituted 1-allyl-N-tosyl-1H-indole-2-carboxamide, N-bromosuccinimide, substituted 10-bromo-3-(bromomethyl)-2-tosyl-3,4-dihydropyrazino[1,2-a]indol-1(2H)-one, (9S)-6′-methoxy-9-[N-[3,5-bis(trifluoromethyl)phenyl]carbamate]cinchonan-9-ol, Quinidine Derivative

by werner@buchler-gmbh.com | Jun 13, 2023

Arylation, quinones, azlactones, (R)-N-(3-benzyl-5-hydroxy-2-oxo-2,3-dihydronaphtho[1,2-b]furan-3-yl)benzamide, 3-[[3,5-bis(trifluoromethyl)phenyl]amino]-4-[[(9S)-6′-methoxycinchonan-9-yl]amino]-3-cyclobutene-1,2-dione, Quinidine Derivative

by werner@buchler-gmbh.com | Jun 9, 2023

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