Isoxazoline Cyclization, substituted 4,4,4-trifluoro-1,3-diphenylbut-2-en-1-one, hydroxylamine, 4-((S)-5-(3,5-dichlorophenyl)-5-(trifluoromethyl)-4,5-dihydroisoxazol-3-yl)-N-((R)-2-ethyl-3-oxoisoxazolidin-4-yl)-2-methylbenzamide, (8α,9R)-(8′′α,9′′R)-1,1′′-[(2,3,5,6-tetrafluoro-1,4-phenylene)bis(methylene)]bis[9-hydroxy-6′-methoxy-cinchonanium bromide, Quinine Derivative by werner@buchler-gmbh.com | Mar 25, 2026
Flow Chemistry, α,β-unsaturated ketones, carbon with two electron-withdrawing groups, β-substituted ketones, Immobilized (8α,9S)-6′-methoxy-3-(1H-1,2,3-triazol-4-yl)-10,11-dinorcinchonan-9-amine, Quinine Derivative by werner@buchler-gmbh.com | Mar 18, 2026
Epoxidation, alkylidenemalononitriles, cumene hydroperoxide, 3-substituted oxirane-2,2-dicarbonitrile, N-[(1S,2S)-2-hydroxy-1,2-diphenylethyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]-thiourea, Quinine Derivative by werner@buchler-gmbh.com | Mar 10, 2026
Michael Addition, azlactones, o-hydroxy chalcones, (R)-2-((S)-1-(5-chloro-2-hydroxyphenyl)-3-(4-iodophenyl)-3-oxopropyl)-2,4-diphenyloxazol-5(2H)-one, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea, Quinine Derivative by werner@buchler-gmbh.com | Jan 19, 2026
Aza-Friedel-Crafts Alkylation, naphthols, isatin‐derived ketimines, aryl indoles, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea, Quinine Derivative by werner@buchler-gmbh.com | Jan 15, 2026
