Epoxidation, tert-butyldimethyl(((8S,13S,14S,17S)-13-methyl-17-(prop-1-yn-1-yl)-1,2,4,6,7,8,12,13,14,15,16,17-dodecahydrospiro[cyclopenta[a]phenanthrene-3,2′-[1,3]dioxolan]-17-yl)oxy)silane, hydrogen peroxide, tert-butyldimethyl(((5’R,8’S,10’R,13’S,14’S,17’S)-13′-methyl-17′-(prop-1-yn-1-yl)-1′,2′,7′,8′,12′,13′,14′,15′,16′,17′-decahydro-4’H,6’H-spiro[[1,3]dioxolane-2,3′-[5,10]epoxycyclopenta[a]phenanthren]-17′-yl)oxy)silane, (8α,9R)-9-hydroxy-6′-methoxy-1-(phenylmethyl)-cinchonanium bromide, Quinine Derivative by werner@buchler-gmbh.com | Mar 18, 2026
Kinetic Resolution, N-protected 4-benzyloxazolidine-2,5-dione, α-amino acids, N-protected (S)-4-benzyloxazolidine-2,5-dione, 1,4-Bis[(9S)-10,11-dihydro-6′-methoxycinchonan-9-yl]-9,10-anthracenedione, Dihydroquinidine Derivative by werner@buchler-gmbh.com | Mar 6, 2025
Allylation, tert-butyl 2-((diphenylmethylene)amino)acetate, trans-substituted allyl acetate, trans-substituted tert-butyl (S)-2-((diphenylmethylene)amino)pent-4-enoate, triphenyl phosphite, di-μ-chlorobis(η3-2-propenyl)di-palladium, 1-(9-anthracenylmethyl)-9-methoxy-(1S,9R)-cinchonanium iodide, Cinchonidine Derivative by werner@buchler-gmbh.com | Jan 22, 2024
Baylis Hillman, (9H-fluoren-9-yl)methyl (S)-(4-methyl-1-oxopentan-2-yl)carbamate, 1,1,1,3,3,3-hexafluoropropan-2-yl acrylate, sodium methanolate, methyl (3S,4S)-4-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-3-hydroxy-6-methyl-2-methyleneheptanoate, (3α,9S)-3,9-epoxy-10,11-dihydro-cinchonan-6′-ol, Dihydrocupreidine Derivative by werner@buchler-gmbh.com | Sep 15, 2023
Desymmetrization, cyclic anhydrides, methanol, (2R,3S)-4-methoxy-2,3-dimethyl-4-oxobutanoic acid, 1,4-Bis[(9S)-10,11-dihydro-6′-methoxycinchonan-9-yl]-9,10-anthracenedione, Dihydroquinidine Derivative by werner@buchler-gmbh.com | Jul 5, 2023
