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Michael Addition, alpha,beta unsaturated ketones, nitromethane, beta-(nitromethyl)-ketones, 3-[[3,5-bis(trifluoromethyl)phenyl]amino]-4- [[(8α,9S)-6′-methoxycinchonan-9-yl]amino]- 3-Cyclobutene-1,2-dione, Quinine Derivative

by Anna-Lena Hartmann | Jul 27, 2022

Domino Michael/Henry reaction (Nitroaldol), alpha-acetyl-gamma-ketoesters, nitroolefins, multisubstituted cyclopentantes, (8α,9R)-6′-Methoxycinchonan-9-amine, Quinine Derivative

by Anna-Lena Hartmann | Jul 27, 2022

Henry (Nitroaldol), 1,1,1-trifluoro-3-phenylpropan-2-one, nitromethane, (S)-1,1,1-trifluoro-2-nitro-3-phenylpropan-2-ol, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9R)-9-[[[[3,5-bis(trifluoromethyl)phenyl]amino]carbonyl]oxy]-10,11-dihydro-6′-methoxycinchonan-5′-yl]-urea, Dihydroquinine Derivative

by Anna-Lena Hartmann | Jul 19, 2022

Spirocyclization: Domino Knoevenagel/Michael/Cyclization, indoline-2,3-diones, malononitrile, beta-diketones, Spiro[4H-pyran-3,3′-oxindoles], Cupreine Base

by Anna-Lena Hartmann | Jul 15, 2022

Michael Addition, dimethyl 2-bromomalonate, (E)-(2-nitrovinyl)benzene, dimethyl (S)-2-bromo-2-(2-nitro-1-phenylethyl)malonate, Cupreine Base

by Anna-Lena Hartmann | Jul 14, 2022

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