Any hydrocarbon or heterocycle with 4n+2 electrons in a fully conjugated cyclic π system is considered to be an...
Buchler Glossary
Sonogashira reaction
The Sonogashira reaction is a cross-coupling reaction used in organic synthesis to form carbon–carbon bonds. It employs a palladium catalyst as well as copper co-catalyst to form a carbon–carbon bond between a terminal alkyne and an aryl or vinyl halide.
Sonogashira reaction examples catalyzed by cinchona alkaloid derivatives can be found in our free of charge Chiral Catalyst Search.
Example from literature
A general asymmetric copper-catalysed Sonogashira C (sp 3)–C (sp) coupling. (Liu et al.; Nat. Chem. 2019, 11(12), 1158-1166.)
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