Any hydrocarbon or heterocycle with 4n+2 electrons in a fully conjugated cyclic π system is considered to be an...
Buchler Glossary
Nazarov cyclization
Nazarov cyclization is one of the most versatile methods for the synthesis of cyclopentenones from vinyl ketones. For the synthesis a stoichiometric Lewis acid or protic acid promoter is used. The key step of the reaction mechanism involves a cationic 4π-electrocyclic ring closure which forms the cyclopentenone product.
Nazarov cyclization examples catalyzed by cinchona alkaloid derivatives can be found in our free of charge Chiral Catalyst Search Data Base.
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