Any hydrocarbon or heterocycle with 4n+2 electrons in a fully conjugated cyclic π system is considered to be an...
Buchler Glossary
Darzens Reaction
Darzens reaction is also known as the Darzens condensation or glycidic ester condensation. It is the chemical reaction of a ketone or aldehyde with an α-haloester in the presence of a base to form an α,β-epoxy ester, also called a “glycidic ester”.
Please find further examples of Darzens reaction promoted by Cinchona Alkaloids in our Buchler Chiral Catalyst Search.
Example from literature
Phase-transfer-catalyzed asymmetric Darzens reaction. (Arai et al.; Tetrahedron 1999, 55, 6375-6386.)
Further Articles:
Asymmetric Aldol Reaction
The aldol reaction is one of the most important and effective methodologies for the straightforward construction of...
Asymmetric Alkylation
Alkylation is the introduction of an alkyl group into an organic compound by substitution or addition. The alkyl group...
Asymmetric Amination
Amination is the process by which an amine group is introduced into an organic molecule. This type of reaction is...
Asymmetric Dihydroxylation
Asymmetric Dihydroxylation of olefins is of high synthetic value because it introduces two vicinal hydroxy groups,...